Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue

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Nov. 4, 2019

SCIENTIFIC

Mounting evidence incriminates tumour-infiltrating myeloid cells as mediators of resistance to checkpoint blockade. Recent preclinical work implicates the physical association of neutrophils & T cells in reducing anti-tumour activity.

https://immunology.sciencemag.org/content/4/40/eaaw9159