Three early stage clinical trials have suggested benefit of adding checkpoint inhibition to BRAF ± MEK inhibitor therapy for patients with advanced BRAF-mutant disease.

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Oct. 21, 2019

SCIENTIFIC

The Pregnancy Initiative, part of the National Institutes of Health Integrative Human Microbiome Project, followed over 1,500 pregnant women longitudinally in the United States through pregnancy, aiming to understand how the microbiome changes during pregnancy and how it may impact the risk of premature birth.
Toxicity was significant but generally manageable. Phase III studies underway.

https://www.nature.com/nm/volumes/25/issues/6